Ligand-aware protein sequence design neural network.
Nature takes millions of years to evolve proteins for specific functions. Experimentally, we can mimic nature's evolution process to engineer proteins for specific functions. Unfortunately, sometimes, they work, mostly, they don't.
Using protein design, the 2024 Nobel prize-winning technology, we can fast-forward the evolution process and push the biomedical research and industry forward. Read more at Research. Get to know Dr. An at About PI.
I will start a new position as an assistant professor at Rice University, BioScience Department, with affiliations to other departments from 2026, and taking rotation students from 2025 Fall! If you are interested in working with me, as an undergraduate RA, technician, graduate RA, or a postdoc, please check out the positions page and contact me at linnaan[at]rice.edu
Computational expertise is preferred but not required. You will be trained in the lab, for both experimental and computational research.
Want to quickly see if you will be interested in joining the lab? Check out the QuickStart page! No prior experience is required.
Ligand-aware protein sequence design neural network.
Ligand-binding and sensing protein design.
Computational sampling of pocket containing proteins.
Mechanism of action study of a unique substrate-assisted enzyme.
Introduction of protein design using the blueprint builder in Rosetta.