Integrate ML and Experiments

Research: Functional Protein Design

Nature takes millions of years to evolve proteins for specific functions. Experimentally, we can mimic nature's evolution process to engineer proteins for specific functions. Unfortunately, sometimes, they work, mostly, they don't.

Using protein design, the 2024 Nobel prize-winning technology, we can fast-forward the evolution process and push the biomedical research and industry forward. Read more at Research. Get to know Dr. An at About PI.

Join a ML4Biochem Team

We are hiring!

I started in January 2026 as an assistant professor in the Department of BioSciences at Rice University, with affiliations in the Department of Bioengineering and the Department of Chemistry. I am also a member of the Ken Kennedy Institute and the Rice Synthetic Biology Institute. If you are interested in working with me as an undergraduate RA, technician, graduate RA, or postdoc, please check out the positions page and contact me at linnaan[at]rice.edu.

Computational expertise is preferred but not required. You will be trained in the lab, for both experimental and computational research.

Want to quickly see if you will be interested in joining the lab? Check out the QuickStart page! No prior experience is required.

Want to join a community doing machine learning for biochemistry? check out ML4BIOCHEM page!